Stereochemistry of the carbon-skeleton rearrangements dependent on coenzyme B12. MNDO quantum chemical calculations
نویسندگان
چکیده
منابع مشابه
Coenzyme B12 (cobalamin)-dependent enzymes.
The B12 or cobalamin coenzymes are complex macrocycles whose reactivity is associated with a unique cobalt-carbon bond. The two biologically active forms are MeCbl and AdoCbl and their closely related cobamide forms. MeCbl participates as the intermediate carrier of activated methyl groups. During the catalytic cycle the coenzyme shuttles between MeCbl and the highly nucleophilic cob(I)alamin f...
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ژورنال
عنوان ژورنال: Journal of the American Chemical Society
سال: 1985
ISSN: 0002-7863,1520-5126
DOI: 10.1021/ja00299a046